G.G.S.I.EYE RESEARCH & CURE CENTRE , DELHI, INDIA
FOR MORE DETAILS CALL 9911060609,
Training courses available at G.G.S.I.EYE Research & Cure Centre
You can order riboflavin complex plus UV-a instrument (Join training course for C3R)
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CORNEAL COLLAGEN CROSSLINKING WITH RIBOFLAVIN (C3R)
The latest revolutionary Keratoconus treatment is C3R (Corneal Collagen
Crosslinking with Riboflavin) that has been proven to strengthen the weak
corneal structure by increasing collagen crosslinking, which
are the natural “anchors” within the cornea. These anchors are responsible for
preventing the cornea from bulging out and becoming steep and irregular,
consequence of advanced Keratoconus.
C3R causes the collagen fibrils to thicken, stiffen, and crosslink & reattach to each other, making the cornea stronger and more stable & halting the progression of the disease.
The Procedure
The C3R treatment is performed in 30 minutes. During the treatment,
custom-made riboflavin eye drops are applied to the cornea, which is then
activated by ultraviolet light
The cornea which is the front transparent structure of the eye is first
anaesthetized using drops. . The mucous surface of the cornea (epithelium) is
disrupted and then Riboflavin, (Vitamin B2) drops are placed in the eye
every few minutes. The yellow pigment of the Riboflavin absorbs the
Ultraviolet A light , increases the amount of collagen cross-linking in
the cornea and strengthen the cornea. . Once the procedure is completed, a soft
bandage contact lens will be placed in the eye and antibiotics will be
instilled. The contact lens will be removed in one or two days.
The cornea increases in rigidity soon after the procedure although the process of cross linking continues on for a period of a few days afterwards. During X-linking new chemical bonds are induced (SEE FIGURE BELOW).
Is Ultraviolet light harmful ?
Ultraviolet A light used in this procedure is not harmful to the eye in measured
doses. Ultraviolet C light (in sunlight) is potentially harmful. The Light
emitting diodes used in the C3R device is of a wavelength that is not harmful.
Furthermore, light emission is carefully measured and calibrated prior to each
treatment. There is also a self diagnostic check on the device which prevents
use in case of a malfunction. There have been concerns about toxicity to the
retina (at the back of the eye) however the Riboflavin pigment in the cornea and
front of the eye, absorbs the Ultraviolet light and in effect stops the light
from being transmitted to the retina.
We have the protective device which tells that your eyes are getting constant wavelength & energy, which is must for these UV A delivering devices, as different wavelength , low or high energy delivered to eye can harm your eyes.
Advantages of C3R
Simple non invasive treatment
Halts the progress as new chemical bonds are
induced and causes some regression
No handling of lenses every day
No stitches
No incisions
Quick recovery
Other treatments
Contact Lenses – RGP Contact Lenses
In mild or early stages, eyeglasses or normal contact lenses may correct the
astigmatic vision. Contact lenses in Keratoconus are not easy to fit, usually
not very comfortable. They need constant maintenance and frequent follow ups
with the doctor. As Keratoconus advances, rigid gas-permeable (RGP) contact
lenses maybe the only non-surgical way to achieve clear vision. But contact lens
fitting of a patient with Keratoconus requires much care and frequent check-ups,
because the condition can worsen. Most importantly, they do not arrest the
progress of disease. Also there can be scarring as a result of contact lens wear
causes problems of its own.
Intacs
It is insertion of intrastromal corneal ring segments. A small incision is made in the periphery of
the cornea and two thin arcs of polymethyl methacrylate slide between the layers
of the corneal stroma on either side of the pupil, the incision then being
closed. The segments push out against the curvature of the cornea, flattening
the peak of the cone and returning it to a more natural shape. However intacs do
not inherently alter the biomechanical structural integrity of the cornea and
thus may not be a permanent solution. If the refraction changes over a period of
time after inserting the intacs rings they would need to be removed. It is not
recommended at our centre for intacs .
Corneal Transplant
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You can order riboflavin complex plus UV-a instrument (Join training course for C3R)