CHALAZION:
A chalazion is a chronic lipogranuloma of an occluded meibomian gland. This non-infectious local inflammation gradually becomes more localized to
form a discrete mass. It often resolves spontaneously within weeks. If it persists, intralesional corticosteroid injection or surgical incision and curettage may be considered.[
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MOLLUSCUM
CONTAGIOSUM: Molluscum contagiosum is a disease of the eyelids caused by the molluscum contagiosum poxvirus. Transmitted by direct contact, molluscum contagiosum is often seen in children; in young adults, it can be spread by sexual transmission.
Usually a single lesion appears beginning as a papule and enlarging to a waxy nodule with an umbilicated center. Immunosuppressed individuals, such as those with AIDS, can develop multiple lesions of the eyelid margins and, rarely, of the conjunctiva.
Patients often present with follicular conjunctivitis, with or without punctate epithelial keratitis, subepithelial infiltrates, and vascular pannus. Preauricular
lymph-adenopathies can be present. Some patients with chronic conjunctivitis may fail to notice a small molluscum contagiosum nodule hidden within the eyelashes.
This infection is usually self-limited, but it can persist for 2 years or more. When it is persistent or when it is complicated by symptomatic keratoconjunctivitis, excision, incision, or Cryotherapy of the lesion may be considered.
VIRAL
PAPILLOMA: A wart, or verruca, is caused by human papillomavirus. A viral eyelid Papilloma typically presents as a painless keratinized cutaneous lesion, usually without inflammation. A wart on the eyelid margin can cause mild papillary conjunctivitis.
A benign squamous cell Papilloma, also known as a "skin tag", can resemble a viral Papilloma. This keratinized, fleshy projection can be either pedunculated or sessile. Other common benign eyelid tumors of the epidermis are seborrheic keratosis and epidermal inclusion cysts.
Excision is not usually necessary in the case of any of these lesions. However, it is considered when histopathologic study is needed for diagnostic confirmation to exclude malignancy, when ocular surface inflammation is present, or when the cosmetic appearance is affected. All of these lesions may recur after excision.
SEBORRHEIC
KERATOSIS: Seborrheic keratosis is seen mainly in elderly individuals, a seborrheic keratosis lesion is usually pigmented, well demarcated, and slightly elevated. It is warty and crushed, and it often has a "stuck-on" appearance, with visible keratotic plugs.
A variant in black and Asian adults is called dermatosis papulosa nigra; it can involve the skin of the eyelids and cheeks.
Although seborrheic keratosis is benign, biopsy is occasionally necessary to exclude a premalignant or malignant lesion. Treatment is usually accomplished by shave excision or Cryotherapy.
XANTHELASMA:
Xanthelasma is yellow-to-tan plaque that often involves the medial portion of the upper and lower eyelids. Microscopically, the superficial dermis contains foamy histiocytes, filled with cholesterol esters.
Typically bilateral, these lesions usually occur in middle-aged or older female patients, but they can occur in younger patients and in males. One-third of younger patients have elevated serum cholesterol, and some may have a hypolipidemia
syndrome. Surgical treatment is usually undertaken for cosmetic reasons, but recurrences are common.